Introduction : Clopidogrel is an oral thienopyridine derivative is capable of inhibiting platelet activation. Clopidogrel is a prodrug that is converted into an active drug by hepatic cytochrome CYP2C19, CYP2C19*2 and ...

Air pollution is one of the most crucial public health concerns over the globe. Car fumes as a major component of the pollution burden is thought to modulate the methylation landscape of the exposed people. to assess the ...

Long-term exposure to air pollution exposure has been reported to be closely associated with the increased cancer risk in humans. Previous studies have associated traffic-related air pollution with genetic/epigenetic changes ...

Breast cancer is considered one of the most heterogeneous diseases that might be difficult to characterize and then to treat. Several research groups worldwide have explored different genetic and epigenetic approaches ...

Cancer remains the major health threat worldwide; therefore, the extensive search for potent cancercontrolling agents are still a big demand. Hepatocellular carcinoma (HCC) is a type of cancer widespread in the developing ...

Apollon, also called Baculoviral IAP Repeat-Containing Protein 6 (BIRC6) or Baculoviral IAP Repeat-containing Ubiquitin Conjugating Enzyme (BRUCE), is an anti-apoptotic protein belonging to the IAP family, which consists ...

Survivin, a member of inhibitor of apoptosis protein family, has become an attractive therapeutic target in cancer due to its selective expression in different malignant tumors. It has a dual function in apoptosis suppression ...